Rafferty, John, Dr

Dr John Rafferty

School of Biosciences

Reader in Structural Biology

Principal Admissions Tutor

j.rafferty@sheffield.ac.uk
+44 114 222 2809

Firth Court

Full contact details

Dr John Rafferty
School of Biosciences
Firth Court
Western Bank
��߲ݴ�ý
S10 2TN

Profile

Career history

2005 - present: Reader in Structural Biology, School of Biosciences, ��߲ݴ�ý Univ
1999 - 2004: Royal Society Olga Kennard Fellow, Mol.Biol.&Biotech.Dept, ��߲ݴ�ý Univ
1996 - 1999: BBSRC David Phillips Research Fellow, Mol.Biol.&Biotech.Dept, ��߲ݴ�ý Univ.
1992 - 1996: PDRA, Mol.Biol. & Biotech. Dept, ��߲ݴ�ý Univ.
1990 - 1991: PDRA, Biochem. & Mol.Biol. Dept, Leeds Univ.
1989 - 1990: PDRA, Biophysics Dept, Leeds Univ.
1986 - 1990: PhD, Biophysics Dept, Leeds Univ.

Research interests

My research interests centre on structural studies of proteins and nucleic acids primarily by X-ray crystallography but also utilizing other biophysical techniques such as NMR, SAXS and electron microscopy.

The work provides detailed 3-dimensional insights into biological macromolecules and their assemblies that can be combined with biochemical and genetic investigations to provide a better understanding of how they function.

Currently my research includes determining structural details of proteins involved in DNA or RNA binding; proteins from bacterial membrane transport systems; toxin & antitoxin proteins; and glycosidic enzymes.

The structure of MatC, with its helices and strands shown as cartoon coils and arrows, and a bound D-malate substrate, shown in stick form.

The protein has a hinged “Venus-flytrap-like” structure, with a cleft where the substrate is coordinated, separating two globular domains (the helices and strands for the first domain are shown in cyan and magenta and for the second domain in red and orange). (Rosa et al. (2019) J. Mol. Biol. 431, 351-367)

DNA & RNA metabolism

Drawing originally from work on E.coli DNA recombination protein RuvA and its DNA junction complex, my group has focussed on the recognition and processing of junction points in DNA.

The work has involved studies of proteins from a diverse range of bacterial and viral sources.

It has also expanded into structural studies of RNA binding proteins from bacterial pathogens and simple eukaryotes that regulate the assembly of the ribosome.

In parallel with the crystallography, we have examined the solution structures by SAXS.

Host-pathogen interactions

Recently we have carried out successful and exciting studies of proteins from the pathogen Campylobacter jejuni, which is the major cause of food poisoning worldwide.

This work has seen structures determined for proteins from the bacterial periplasm responsible for metabolite transport across the inner membrane, protein folding & establishment of the outer membrane and mechanisms for avoiding the host immune system.

The work has been extended to examine proteins from the periplasm of other organisms such as Rhodopseudomonas palustris, which is of interest because of its potential biotechnological role in lignin processing.

Glycoside recognition and processing

The carbohydrate coat on many cells provides both a protective role but also a nutrient source for invading organisms.

We have been studying the structural determinants that control the way key enzymes and associated binding domains recognize specific targets and process them.

These proteins in pathogenic organisms provide potentially excellent targets for inhibition and the development of antibacterial compounds.

Publications

Show: Featured publications All publications

Featured publications

Journal articles

Phansopa C, Roy S, Rafferty JB, Douglas CWI, Pandhal J, Wright PC, Kelly DJ & Stafford GP (2014) . Biochem J, 458(3), 499-511.
Green V, Curtis FA, Sedelnikova S, Rafferty JB & Sharples GJ (2013) . Mol Microbiol, 89(6), 1240-1258.
Afonso JP, Chintakayala K, Suwannachart C, Sedelnikova S, Giles K, Hoyes JB, Soultanas P, Rafferty JB & Oldham NJ (2013) . Nucleic Acids Res, 41(9), 5115-5126.
Salmon RC, Cliff MJ, Rafferty JB & Kelly DJ (2013) . PLoS One, 8(3), e59844.
Canas C, Carrasco B, Garcia-Tirado E, Rafferty JB, Alonso JC & Ayora S (2011) . J MOL BIOL, 410(1), 39-49.
Kale A, Phansopa C, Suwannachart C, Craven CJ, Rafferty JB & Kelly DJ (2011) . J Biol Chem, 286(24), 21254-21265.
Roujeinikova A, Simon WJ, Gilroy J, Rice DW, Rafferty JB & Slabas AR (2007) . J Mol Biol, 365(1), 135-145.
Macmaster R, Sedelnikova S, Baker PJ, Bolt EL, Lloyd RG & Rafferty JB (2006) . Nucleic Acids Res, 34(19), 5577-5584.
Thaw P, Sedelnikova SE, Muranova T, Wiese S, Ayora S, Alonso JC, Brinkman AB, Akerboom J, van der Oost J & Rafferty JB (2006) . Nucleic Acids Res, 34(5), 1439-1449.
Rafferty JB, Bolt EL, Muranova TA, Sedelnikova SE, Leonard P, Pasquo A, Baker PJ, Rice DW, Sharples GJ & Lloyd RG (2003) . Structure, 11(12), 1557-1567.
Kehoe LE, Snidwongse J, Courvalin P, Rafferty JB & Murray IA (2003) . J Biol Chem, 278(32), 29963-29970.
Bailey S, Sedelnikova SE, Mesa P, Ayora S, Waltho JP, Ashcroft AE, Baron AJ, Alonso JC & Rafferty JB (2003) . J Biol Chem, 278(17), 15304-15312.
Abdelghany HM, Bailey S, Blackburn GM, Rafferty JB & McLennan AG (2003) . J BIOL CHEM, 278(7), 4435-4439.

All publications

Journal articles

Alrafaie AM, Pyrzanowska K, Smith EM, Partridge DG, Rafferty J, Mesnage S, Shepherd J & Stafford GP (2024) . Virus Research, 347, 199426-199426.
Curry E, Sedelnikova S, Rafferty J, Hulley M, Pohle M, Muir G & Brown A (2024) . Biotechnology Journal, 19(6).
Bennison DJ, Nakamoto JA, Craggs TD, Milón P, Rafferty JB & Corrigan RM (2021) . mBio.
Churchill-Angus AM, Schofield THB, Marlow TR, Sedelnikova SE, Wilson JS, Rafferty JB & Baker PJ (2021) . Scientific Reports, 11(1).
Wilson JS, Churchill-Angus AM, Davies SP, Sedelnikova SE, Tzokov SB, Rafferty JB, Bullough PA, Bisson C & Baker PJ (2019) . Nature Communications, 10(1).
Ji S, Dix SR, Aziz AA, Sedelnikova SE, Baker PJ, Rafferty JB, Bullough PA, Tzokov SB, Agirre J, Li F-L & Rice DW (2019) . Journal of Biological Chemistry, 294(48), 18077-18091.
Rosa LT, Dix SR, Rafferty JB & Kelly DJ (2019) . Journal of Molecular Biology, 431(2), 351-367.
Rosa LT, Dix SR, Rafferty JB & Kelly DJ (2017) . FEBS Journal.
Khavnekar S, Dantu SC, Sedelnikova S, Ayora S, Rafferty J & Kale A (2017) . Nucleic Acids Research, 45(2), 975-986.
AlMalki FA, Flemming CS, Zhang J, Feng M, Sedelnikova SE, Ceska T, Rafferty JB, Sayers JR & Artymiuk PA (2016) . Nature Structural and Molecular Biology, 23, 640-646.
Phansopa C, Roy S, Rafferty JB, Douglas CWI, Pandhal J, Wright PC, Kelly DJ & Stafford GP (2014) . Biochem J, 458(3), 499-511.
Green V, Curtis FA, Sedelnikova S, Rafferty JB & Sharples GJ (2013) . Mol Microbiol, 89(6), 1240-1258.
Afonso JP, Chintakayala K, Suwannachart C, Sedelnikova S, Giles K, Hoyes JB, Soultanas P, Rafferty JB & Oldham NJ (2013) . Nucleic Acids Res, 41(9), 5115-5126.
Salmon RC, Cliff MJ, Rafferty JB & Kelly DJ (2013) . PLoS One, 8(3), e59844.
Abd Aziz AG, Sedelnikova SE, Ruzheinikov SN, Thorpe S, Mohamed R, Nathan S, Rafferty JB, Baker PJ & Rice DW (2012) . Acta Crystallogr Sect F Struct Biol Cryst Commun, 68(Pt 8), 917-922.
Canas C, Carrasco B, Garcia-Tirado E, Rafferty JB, Alonso JC & Ayora S (2011) . J MOL BIOL, 410(1), 39-49.
Kale A, Phansopa C, Suwannachart C, Craven CJ, Rafferty JB & Kelly DJ (2011) . J Biol Chem, 286(24), 21254-21265.
Fahy E, Carroll J, Rafferty J, Roantree V, Reid C, Norman M & Clarke S (2011) . Biology & Environment: Proceedings of the Royal Irish Academy, 110(2), 95-108.
Muench SP, Prigge ST, McLeod R, Rafferty JB, Kirisits MJ, Roberts CW, Mui EJ & Rice DW (2007) . Acta Crystallogr D Biol Crystallogr, 63(Pt 3), 328-338.
Roujeinikova A, Simon WJ, Gilroy J, Rice DW, Rafferty JB & Slabas AR (2007) . J Mol Biol, 365(1), 135-145.
Macmaster R, Sedelnikova S, Baker PJ, Bolt EL, Lloyd RG & Rafferty JB (2006) . Nucleic Acids Res, 34(19), 5577-5584.
Thaw P, Sedelnikova SE, Muranova T, Wiese S, Ayora S, Alonso JC, Brinkman AB, Akerboom J, van der Oost J & Rafferty JB (2006) . Nucleic Acids Res, 34(5), 1439-1449.
McGregor N, Ayora S, Sedelnikova S, Carrasco B, Alonso JC, Thaw P & Rafferty J (2005) . Structure, 13(9), 1341-1351.
Dickman MJ, Sedelnikova SE, Rafferty JB & Hornby DP (2004) . J Biochem Biophys Methods, 58(1), 39-48.
Rafferty JB, Bolt EL, Muranova TA, Sedelnikova SE, Leonard P, Pasquo A, Baker PJ, Rice DW, Sharples GJ & Lloyd RG (2003) . Structure, 11(12), 1557-1567.
Muranova TA, Sedelnikova SE, Leonard PM, Pasquo A, Bolt EL, Lloyd RG & Rafferty JB (2003) . Acta Crystallogr D Biol Crystallogr, 59(Pt 12), 2262-2264.
Santos-Sierra S, Lemonnier M, Nuñez B, Hargreaves D, Rafferty J, Giraldo R, Andreu JM & Dı́az-Orejas R (2003) . Plasmid, 50(2), 120-130.
Kehoe LE, Snidwongse J, Courvalin P, Rafferty JB & Murray IA (2003) . J Biol Chem, 278(32), 29963-29970.
Muench SP, Rafferty JB, McLeod R, Rice DW & Prigge ST (2003) . Acta Crystallogr D Biol Crystallogr, 59(Pt 7), 1246-1248.
Bailey S, Sedelnikova SE, Mesa P, Ayora S, Alonso JC & Rafferty JB (2003) . Acta Crystallogr D Biol Crystallogr, 59(Pt 6), 1090-1092.
Bailey S, Sedelnikova SE, Mesa P, Ayora S, Waltho JP, Ashcroft AE, Baron AJ, Alonso JC & Rafferty JB (2003) . J Biol Chem, 278(17), 15304-15312.
Abdelghany HM, Bailey S, Blackburn GM, Rafferty JB & McLennan AG (2003) . J BIOL CHEM, 278(7), 4435-4439.
Slabas AR, Kroon JTM, Scheirer TP, Gilroy JS, Hayman M, Rice DW, Turnbull AP, Rafferty JB, Fawcett T & Simon WJ (2002) . J BIOL CHEM, 277(46), 43918-43923.
Dickman MJ, Ingleston SM, Sedelnikova SE, Rafferty JB, Lloyd RG, Grasby JA & Hornby DP (2002) . Eur J Biochem, 269(22), 5492-5501.
Ettema TJG, Brinkman AB, Tani TH, Rafferty JB & van der Oost J (2002) . J BIOL CHEM, 277(40), 37464-37468.
Hargreaves D, Santos-Sierra S, Giraldo R, Sabariegos-Jareño R, de la Cueva-Méndez G, Boelens R, Díaz-Orejas R & Rafferty JB (2002) . Structure, 10(10), 1425-1433.
Roujeinikova A, Baldock C, Simon WJ, Gilroy J, Baker PJ, Stuitje AR, Rice DW, Slabas AR & Rafferty JB (2002) . Structure, 10(6), 825-835.
Bailey S, Sedelnikova SE, Blackburn GM, Abdelghany HM, Baker PJ, McLennan AG & Rafferty JB (2002) . Structure, 10(4), 589-600.
Bailey S, Sedelnikova SE, Blackburn GM, Abdelghany HM, McLennan AG & Rafferty JB (2002) . Acta Crystallogr D Biol Crystallogr, 58(Pt 3), 526-528.
Roujeinikova A, Baldock C, Simon WJ, Gilroy J, Baker PJ, Stuitje AR, Rice DW, Rafferty JB & Slabas AR (2002) . Acta Crystallogr D Biol Crystallogr, 58(Pt 2), 330-332.
Hargreaves D, Giraldo R, Santos-Sierra S, Boelens R, Rice DW, Díaz Orejas R & Rafferty JB (2002) . Acta Crystallogr D Biol Crystallogr, 58(Pt 2), 355-358.
Abdelghany HM, Gasmi L, Cartwright JL, Bailey S, Rafferty JB & McLennan AG (2001) Cloning, characterisation and crystallisation of a diadenosine 5 ',5 '''-P-1,P-4-tetraphosphate pyrophosphohydrolase from Caenorhabditis elegans. BBA-PROTEIN STRUCT M, 1550(1), 27-36.
Showell C, Rafferty JB & Cunliffe VT (2001) Functional studies of the Xenopus Polycomb-group proteins Xeed and XEz.. DEV BIOL, 235(1), 262-263.
Sedelnikova SE, Smits SH, Leonard PM, Brinkman AB, van der Oost J, Rafferty JB & Rice DW (2001) . Acta Crystallogr D Biol Crystallogr, 57(Pt 6), 886-888.
Levy CW, Baldock C, Wallace AJ, Sedelnikova S, Viner RC, Clough JM, Stuitje AR, Slabas AR, Rice DW & Rafferty JB (2001) . J Mol Biol, 309(1), 171-180.
Turnbull AP, Rafferty JB, Sedelnikova SE, Slabas AR, Schierer TP, Kroon JT, Simon JW, Fawcett T, Nishida I, Murata N & Rice DW (2001) . Structure, 9(5), 347-353.
Turnbull AP, Rafferty JB, Sedelnikova SE, Slabas AR, Schierer TP, Kroon JT, Nishida I, Murata N, Simon JW & Rice DW (2001) . Acta Crystallogr D Biol Crystallogr, 57(Pt 3), 451-453.
Leonard PM, Smits SH, Sedelnikova SE, Brinkman AB, de Vos WM, van der Oost J, Rice DW & Rafferty JB (2001) . EMBO J, 20(5), 990-997.
McLeod R, Muench SP, Rafferty JB, Kyle DE, Mui EJ, Kirisits MJ, Mack DG, Roberts CW, Samuel BU, Lyons RE , Dorris M et al (2001) Triclosan inhibits the growth of Plasmodium falciparum and Toxoplasma gondii by inhibition of apicomplexan Fab I. INT J PARASITOL, 31(2), 109-113.
Slabas AR, Simon WR, Schierer T, Kroon J, Fawcett T, Hayman M, Gilroy J, Nishida I, Murata N, Rafferty J , Turnbull A et al (2000) . Biochemical Society Transactions, 28(6), 677-679.
Hayman MW, Fawcett T, Schierer TF, Simon JW, Kroon JTM, Gilroy JS, Rice DW, Rafferty J, Turnbull AP, Sedelnikova SE & Slabas AR (2000) . Biochemical Society Transactions, 28(6), 680-681.
Hayman MW, Fawcett T, Schierer TF, Simon JW, Kroon JTM, Gilroy JS, Rice DW, Rafferty J, Turnbull AP, Sedelnikova SE & Slabas AR (2000) . Biochemical Society Transactions, 28(6), 680-680.
Slabas AR, Simon WR, Schierer T, Kroon J, Fawcett T, Hayman M, Gilroy J, Nishida I, Murata N, Rafferty J , Turnbull A et al (2000) . Biochemical Society Transactions, 28(6), 677-677.
Fisher M, Kroon JT, Martindale W, Stuitje AR, Slabas AR & Rafferty JB (2000) . Structure, 8(4), 339-347.
Fisher M, Sedelnikova SE, Martindale W, Thomas NC, Simon JW, Slabas AR & Rafferty JB (2000) . Acta Crystallogr D Biol Crystallogr, 56(Pt 1), 86-88.
Roujeinikova A, Levy CW, Rowsell S, Sedelnikova S, Baker PJ, Minshull CA, Mistry A, Colls JG, Camble R, Stuitje AR , Slabas AR et al (1999) . J Mol Biol, 294(2), 527-535.
Roujeinikova A, Sedelnikova S, de Boer GJ, Stuitje AR, Slabas AR, Rafferty JB & Rice DW (1999) . J Biol Chem, 274(43), 30811-30817.
Levy CW, Roujeinikova A, Sedelnikova S, Baker PJ, Stuitje AR, Slabas AR, Rice DW & Rafferty JB (1999) Molecular basis of triclosan activity. NATURE, 398(6726), 383-384.
de Boer GJ, Pielage GJA, Nijkamp HJJ, Slabas AR, Rafferty JB, Baldock C, Rice DW & Stuitje AR (1999) Molecular genetic analysis of enoyl-acyl carrier protein reductase inhibition by diazaborine. MOL MICROBIOL, 31(2), 443-450.
Hargreaves D, Rafferty JB, Sedelnikova SE, Lloyd RG & Rice DW (1999) . Acta Crystallogr D Biol Crystallogr, 55(Pt 1), 263-265.
Baldock C, Rafferty JB, Stuitje AR, Slabas AR & Rice DW (1998) . J Mol Biol, 284(5), 1529-1546.
Hargreaves D, Rice DW, Sedelnikova SE, Artymiuk PJ, Lloyd RG & Rafferty JB (1998) . Nat Struct Biol, 5(6), 441-446.
Baldock C, de Boer GJ, Rafferty JB, Stuitje AR & Rice DW (1998) . Biochem Pharmacol, 55(10), 1541-1549.
Rafferty JB, Fisher M, Langridge SJ, Martindale W, Thomas NC, Simon JW, Bithell S, Slabas AR & Rice DW (1998) . Acta Crystallogr D Biol Crystallogr, 54(Pt 3), 427-429.
Rafferty JB, Ingleston SM, Hargreaves D, Artymiuk PJ, Sharples GJ, Lloyd RG & Rice DW (1998) . J Mol Biol, 278(1), 105-116.
Rice DW, Rafferty JB, Artymiuk PJ & Lloyd RG (1997) . Curr Opin Struct Biol, 7(6), 798-803.
Sedelnikova SE, Rafferty JB, Hargreaves D, Mahdi AA, Lloyd RG & Rice DW (1997) . Acta Crystallogr D Biol Crystallogr, 53(Pt 1), 122-124.
Baldock C, Rafferty JB, Sedelnikova SE, Baker PJ, Stuitje AR, Slabas AR, Hawkes TR & Rice DW (1996) . Science, 274(5295), 2107-2110.
Slabas AR, Brown AP, Rafferty JB, Rice DW, Baldock C, Kroon JTM, Simon W, Stuitje AR & Brough CL (1996) Soluble and membrane bound components of plant lipid synthesis. CR ACAD SCI III-VIE, 319(11), 1043-1047.
Baldock C, Rafferty JB, Sedelnikova SE, Bithell S, Stuitje AR, Slabas AR & Rice DW (1996) . Acta Crystallogr D Biol Crystallogr, 52(Pt 6), 1181-1184.
Rafferty JB, Sedelnikova SE, Hargreaves D, Artymiuk PJ, Baker PJ, Sharples GJ, Mahdi AA, Lloyd RG & Rice DW (1996) . Science, 274(5286), 415-421.
Rafferty JB, Simon JW, Baldock C, Artymiuk PJ, Baker PJ, Stuitje AR, Slabas AR & Rice DW (1995) . Structure, 3(9), 927-938.
SOMERS WS, RAFFERTY JB, PHILLIPS K, STRATHDEE S, HE Y-Y, McNALLY T, MANFIELD I, NAVRATIL O, OLD IG, SAINT-GIRONS I , STOCKLEY PG et al (1994) . Annals of the New York Academy of Sciences, 726(1 DNA Damage), 105-117.
Rafferty JB, Simon JW, Stuitje AR, Slabas AR, Fawcett T & Rice DW (1994) . J Mol Biol, 237(2), 240-242.
Wright CE, Raffertya JB, Flower DR, Groom CR, Findlay JBC, North ACT, Phillips SEV & Zagalsky PF (1992) . Journal of Molecular Biology, 224(1), 283-284.
Phillips SEV, Manfield I, Parsons I, Davidson BE, Rafferty JB, Somers WS, Margarita D, Cohen GN, Saint-Girons I & Stockley PG (1989) . Nature, 341(6244), 711-715.
Rafferty JB, Somers WS, Saint-Girons I & Phillips SEV (1989) . Nature, 341(6244), 705-710.
Rafferty JB, Phillips SEV, Rojas C, Boulot G, Saint-girons I, Guillou Y & Cohen GN (1988) . Journal of Molecular Biology, 200(1), 217-219.
Kaushik A, Than T, Petela NJ, Voulgaris M, Percival C, Daniels P, Rafferty JB, Nasmyth KA & Hu B () . Nature Communications, 14(1).
Satur MJ, Urbanowicz P, Spencer DR, Rafferty JB & Stafford GP () . Biochemical Journal.
Bisson C, Salmon RC, West L, Rafferty JB, Hitchcock A, Thomas GH & Kelly DJ () . The FEBS Journal.

Chapters

Brown AP, Slabas AR & Rafferty JB (2009) , Lipids in Photosynthesis (pp. 11-34). Springer Netherlands
Simon JW, Gilroy J, Roujenikova A, Rafferty J, Baldock C, Baker PJ, Rice DW, Stuitje AR & Slabas AR (2003) , Advanced Research on Plant Lipids (pp. 139-142). Springer Netherlands
Slabas AR, Rafferty J, Rice D, Baldock C, Simon JW, Thomas N, Bithell S & Stuitje AR (1997) , Physiology, Biochemistry and Molecular Biology of Plant Lipids (pp. 38-41). Springer Netherlands
Slabas AR, Brough C, Kroon J, Simon W, Swinhoe R, Rice D, Rafferty J, Winz R, Stuitjet AR & Elborough K (1995) , Plant Lipid Metabolism (pp. 55-57). Springer Netherlands

Conference proceedings papers

Roujeinikova A, Simon WJ, Gilroy J, Rice DW, Rafferty JB & Slabas AR (2007) Structures of fatty acyl-( acyl carrier protein) thioesters reveal a binding cavity that expands to fit longer substrates. FEBS JOURNAL, Vol. 274 (pp 223-223)
Bailey S, Abdelghany HM, Sedelnikova SE, Blackburn GM, Baker PJ, Rafferty JB & McLennan AG (2002) Crystal structure and mutational analysis of the diadenosine tetraphosphate (Ap4A) 'Nudix' hydrolase from Caenorhabditis elegans. DRUG DEVELOPMENT RESEARCH, Vol. 56(4) (pp 567-567)
Slabas AR, Hanley ZAC, Schierer TED, Rice D, Turnbull A, Rafferty J, Simon B & Brown A (2001) . Journal of Plant Physiology, Vol. 158(4) (pp 505-513)
Fisher M, Martindale W, Slabas AR, Rice DW & Rafferty JB (1999) CRYSTALLOGRAPHIC STUDIES OF THE NADP-DEPENDENT beta-KETO ACP REDUCTASE FROM ESCHERICHIA COLI. ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES, Vol. 55 (pp 293-294)

Preprints

Curry E, Sedelnikova S, Rafferty J, Hulley M & Brown A (2024) , Cold Spring Harbor Laboratory.
Hu B, Kaushik A, Than T, Petela N, Voulgaris M, Percival C, Daniels P, Rafferty J & Nasmyth K (2022) , Research Square Platform LLC.
Kaushik A, Than T, Petela NJ, Voulgaris M, Percival C, Daniels P, Rafferty JB, Nasmyth KA & Hu B (2022) , Cold Spring Harbor Laboratory.
Bennison DJ, Nakamoto JA, Craggs TD, Milón P, Rafferty JB & Corrigan RM () , Cold Spring Harbor Laboratory.

Teaching activities

Level 3 modules

MBB344 Genomic Science
MBB362 Biochemistry Data Handling

Level 2 modules

MBB261 Biochemistry 2
MBB265 Practical Molecular Bioscience 2

Level 1 modules

MBB161 Biochemistry (Module Coordinator)
MBB165 Practical Molecular Bioscience 1

���߲ݴ�ý

School of Biosciences

School of Biosciences

Dr John Rafferty

Career history

DNA & RNA metabolism

Host-pathogen interactions

Glycoside recognition and processing

Featured publications

Journal articles

All publications

Journal articles

Chapters

Conference proceedings papers

Preprints

Level 3 modules

Level 2 modules

Level 1 modules

��߲ݴ�ý