Dr Victoria C Ridger

BSc PhD PGCertHE FHEA

Clinical Medicine, School of Medicine and Population Health

Senior Lecturer in Vascular Biology

Course Lead for MRes in Cardiovascular Medicine: From Molecules to Man

Departmental Director of Education

v.c.ridger@sheffield.ac.uk
+44 114 215 9549

Full contact details

Dr Victoria C Ridger
Clinical Medicine, School of Medicine and Population Health
The Medical School
Beech Hill Road
º¬Ð߲ݴ«Ã½
S10 2RX
Profile

For enquiries please contact - ClinMed-Operational@sheffield.ac.uk

I obtained an honours degree in Pharmacology from King´s College, London in 1994 during which time I spent a year in the lab of Professor W James Metzger in North Carolina.

The project I undertook was investigating the inhibition of VLA-4 in asthmatic responses in a rabbit model and this, together with my PhD project carried out under the supervision of Professor Susan Brain, ignited my interest in inflammation.

My first postdoctoral position was at the NHLI, Imperial College, London in 1997 working with Professors Tim Williams and Ian Sabroe.

I then moved to the Department of Cardiovascular Science at the University of º¬Ð߲ݴ«Ã½ in 1998 to take up a Wellcome Trust funded postdoctoral position with Professor Paul Hellewell. This project involved establishing a mouse model of lung inflammation in order to investigate CD18-independent neutrophil trafficking.

In 2000 I started my third postdoctoral project with Dr Keith Norman and Professor Paul Hellewell investigating adhesion molecule interactions using microspheres in a mouse intravital microscopy model.

I was awarded a BHF Intermediate Fellowship in 2002 and was then successful in gaining a New Blood Lectureship, which I started at the end of my Fellowship in 2005. In 2016 I was promoted to Senior Lecturer.

Research interests

My major research interests are in leukocyte trafficking and, in particular, mechanisms of adhesion and migration in the lung and cardiovascular system.

Neutrophils are important cells involved in many inflammatory diseases but their involvement in atherosclerosis and atherogenesis remains unclear. Many of the factors shown to be important players in atherosclerosis are also known to be involved in regulating neutrophil recruitment to sites of injury.

During the course of my second postdoctoral position, I established a novel method for the isolation of pure populations of unactivated murine peripheral blood neutrophils.

I carried out this work with a British Heart Foundation (BHF) funded PhD student whom I directly supervised. The use of these isolated cells has proved invaluable in investigating the role of these cells in inflammatory processes.

The award of my BHF Intermediate Fellowship allowed me to focus on direct investigation of the interaction of neutrophils and monocytes with the endothelium in large blood vessels where atherosclerosis predominantly occurs.

At the same time, my BHF funded PhD student investigated the role of NO in leukocyte-endothelial interactions using flow cytometry and an in vitrochemotaxis assay. During these investigations, we discovered that inhibiting the formation of NO through NOS inhibition with L-NAME resulted in the production of microparticles by neutrophils.

These studies furthered my interest in the role of neutrophil-derived microparticles in augmenting the inflammatory response and, more specifically an interest in their potential role in atherosclerosis. I am particularly interested in elucidating the role of neutrophils in vascular inflammation and, more specifically, neutrophil-derived microparticles on progression of atherosclerotic plaque formation, lung inflammation and neurodegenerative diseases.

I have recently been awarded a number of BHF funded Grants to investigate these aspects of neutrophils function, one of which is to carry out cutting-edge intravital imaging of the carotid in Professor Marc van Zandvoort’s group at the University of Maastricht.

I currently have collaborations with Dr Helen Philippou and Dr Robert Ariens at the University of Leeds investigating in vivo thrombus formation in the femoral vein. I also work closely with Dr Julie Simpson in SITraN investigating the role of neutrophil microvesicles in neuroinflammation, studies funded by Alzheimer’s Research.

Current projects:

  • Affimers targeting multiple anti-fibrinolytic proteins for the management of the enhanced thrombotic environment in diabetes. Diabetes Research UK (2019-2021).
  • Role of Fibrin Biofilm and Clot Network Architecture in Thrombus Stability. British Heart Foundation Programme Grant (2019-2024).
  • Do neutrophil microvesicles play a role in atherosclerotic plaque erosion? University of º¬Ð߲ݴ«Ã½ Faculty PGT-PGR Scholarship (2018-2021).
  • Neutrophil-derived microvesicle-induced blood brain barrier dysfunction and white matter lesion formation in the ageing brain. Alzheimer's Research UK Studentship (2016-2019).
  • Neutrophil derived microvesicles: linking systemic inflammation and dementia. Alzheimer’s Research UK Pilot Grant (2018-2019).
  • Role of neutrophil microvesicles in lung inflammation. Departmental Nodal Studentship (2016-2019).
Publications

Show: Featured publications All publications

Journal articles

  • Gomez I, Ward B, Souilhol C, Recarti C, Ariaans M, Johnston J, Burnett A, Mahmoud M, Luong LA, West L , Long M et al (2020) . Nature Communications, 11(1). RIS download Bibtex download
  • Souilhol C, Serbanovic-Canic J, Fragiadaki M, Chico TJ, Ridger V, Roddie H & Evans PC (2020) . Nature Reviews Cardiology, 17(1), 52-63. RIS download Bibtex download
  • Ajikumar A, Long MB, Heath PR, Wharton SB, Ince PG, Ridger VC & Simpson JE (2019) . International Journal of Molecular Sciences, 20(20). RIS download Bibtex download
  • Souilhol C, Gauci I, Feng S, Tardajos Ayllon B, Mahmoud M, Canham L, Fragiadaki M, Serbanovic-Canic J, Ridger V & Evans PC (2019) . Cardiovascular Research. RIS download Bibtex download
  • Xanthis I, Souilhol C, Serbanovic-Canic J, Roddie H, Kalli AC, Fragiadaki M, Wong R, Shah DR, Askari JA, Canham L , Akhtar N et al (2019) . Journal of Cell Science. RIS download Bibtex download
  • Feng S, Bowden N, Fragiadaki M, Souilhol C, Hsiao S, Mahmoud M, Allen S, Pirri D, Ayllon BT, Akhtar S , Thompson AAR et al (2017) . Arteriosclerosis, Thrombosis, and Vascular Biology, 37(11), 2087-2101. RIS download Bibtex download
  • Ridger VC, Boulanger CM, Angelillo-Scherrer A, Badimon L, Blanc-Brude O, Bochaton-Piallat M-L, Boilard E, Buzas EI, Caporali A, Dignat-George F , Evans PC et al (2017) . Thromb Haemost, 117(7), 1296-1316. RIS download Bibtex download
  • Burnett A, Gomez I, De Leon D, Ariaans M, Progias P, Kammerer R, Velasco G, Marron M, Hellewell P & Ridger V (2017) . Scientific Reports, 7. RIS download Bibtex download
  • Serbanovic-Canic J, de Luca A, Warboys C, Ferreira PF, Luong LA, Hsiao S, Gauci I, Mahmoud M, Feng S, Souilhol C , Bowden N et al (2016) . Arteriosclerosis, Thrombosis, and Vascular Biology, 37(1), 130-143. RIS download Bibtex download
  • Mahmoud M, Kim HR, Xing R, Hsiao S, Mammmoto A, Chen J, Serbanovic-Canic J, Feng S, Bowden NP, Maguire R , Ariaans M et al (2016) . Circulation Research, 119, 450-462. RIS download Bibtex download
  • Duval C, Ali M, Chaudhry WW, Ridger VC, Ariëns RAS & Philippou H (2016) . Arteriosclerosis, Thrombosis, and Vascular Biology, 36(2), 308-316. RIS download Bibtex download
  • Domingues MM, Macrae FL, Duval C, McPherson HR, Bridge KI, Ajjan RA, Ridger VC, Connell SD, Philippou H & Ariens RAS (2016) . Blood, 127(4), 487-495. RIS download Bibtex download
  • Alfaidi M, Wilson H, Daigneault M, Burnett A, Ridger V, Chamberlain J & Francis SE (2015) . Journal of Biological Chemistry, 290, 24067-24078. RIS download Bibtex download
  • Alsharif KF, Thomas MR, Judge HM, Khan H, Prince LR, Sabroe I, Ridger VC & Storey RF (2015) . Vascular Pharmacology, 71, 201-207. RIS download Bibtex download
  • Duval C, Allan P, Connell SD, Ridger VC, Philippou H & Ariëns RA (2014) . Thrombosis and Haemostasis, 111(5), 842-850. RIS download Bibtex download

All publications

Journal articles

  • Souilhol C, Tardajos Ayllon B, Li X, Diagbouga MR, Zhou Z, Canham L, Roddie H, Pirri D, Chambers EV, Dunning MJ , Ariaans M et al (2022) . Science Advances, 8(35). RIS download Bibtex download
  • Lodge KM, Vassallo A, Liu B, Long M, Tong Z, Newby PR, Agha-Jaffar D, Paschalaki K, Green CE, Belchamber KBR , Ridger VC et al (2022) . American Journal of Respiratory and Critical Care Medicine. RIS download Bibtex download
  • Dow R & Ridger V (2021) . The International Journal of Biochemistry & Cell Biology, 141. RIS download Bibtex download
  • McPherson HR, Duval C, Baker SR, Hindle MS, Cheah LT, Asquith NL, Domingues MM, Ridger VC, Connell SDA, Naseem KM , Philippou H et al (2021) . eLife, 10. RIS download Bibtex download
  • Duval C, Baranauskas A, Feller T, Ali M, Cheah LT, Yuldasheva NY, Baker SR, McPherson HR, Raslan Z, Bailey MA , Cubbon RM et al (2021) . Proceedings of the National Academy of Sciences, 118(27). RIS download Bibtex download
  • Mahmoud MM, Serbanovic-Canic J, Feng S, Souilhol C, Xing R, Hsiao S, Mammoto A, Chen J, Ariaans M, Francis SE , Van der Heiden K et al (2020) . Scientific Reports, 10(1). RIS download Bibtex download
  • Gomez I, Ward B, Souilhol C, Recarti C, Ariaans M, Johnston J, Burnett A, Mahmoud M, Luong LA, West L , Long M et al (2020) . Nature Communications, 11(1). RIS download Bibtex download
  • Souilhol C, Serbanovic-Canic J, Fragiadaki M, Chico TJ, Ridger V, Roddie H & Evans PC (2020) . Nature Reviews Cardiology, 17(1), 52-63. RIS download Bibtex download
  • Ajikumar A, Long MB, Heath PR, Wharton SB, Ince PG, Ridger VC & Simpson JE (2019) . International Journal of Molecular Sciences, 20(20). RIS download Bibtex download
  • Souilhol C, Gauci I, Feng S, Tardajos Ayllon B, Mahmoud M, Canham L, Fragiadaki M, Serbanovic-Canic J, Ridger V & Evans PC (2019) . Cardiovascular Research. RIS download Bibtex download
  • Xanthis I, Souilhol C, Serbanovic-Canic J, Roddie H, Kalli AC, Fragiadaki M, Wong R, Shah DR, Askari JA, Canham L , Akhtar N et al (2019) . Journal of Cell Science. RIS download Bibtex download
  • Ajikumar A, Ridger V, Heath P, Wharton S, Ince P & Simpson JE (2018) . Alzheimer's & Dementia, 14(7S_Part_27), P1455-P1455. RIS download Bibtex download
  • Feng S, Fragiadaki M, Souilhol C, Ridger V & Evans PC (2017) . Arteriosclerosis, Thrombosis, and Vascular Biology, 37(12), e199-e200. RIS download Bibtex download
  • Luong L, Duckles H, Schenkel T, Mahmoud M, Lopez-Tremoleda JL, Wylezinska-Arridge M, Ali M, Bowden NP, Villa-Uriol M, van der Heiden K , Xing R et al (2017) . Thrombosis and Haemostasis, 116(1), 181-190. RIS download Bibtex download
  • Feng S, Bowden N, Fragiadaki M, Souilhol C, Hsiao S, Mahmoud M, Allen S, Pirri D, Ayllon BT, Akhtar S , Thompson AAR et al (2017) . Arteriosclerosis, Thrombosis, and Vascular Biology, 37(11), 2087-2101. RIS download Bibtex download
  • Mahmoud M, Serbanovic-Canic J, Feng S, Souilhol C, Xing R, Hsiao S, Mammoto A, Chen J, Ariaans M, Francis S , Van der Heiden K et al (2017) . Scientific Reports, 7. RIS download Bibtex download
  • Ridger VC, Boulanger CM, Angelillo-Scherrer A, Badimon L, Blanc-Brude O, Bochaton-Piallat M-L, Boilard E, Buzas EI, Caporali A, Dignat-George F , Evans PC et al (2017) . Thromb Haemost, 117(7), 1296-1316. RIS download Bibtex download
  • Burnett A, Gomez I, De Leon D, Ariaans M, Progias P, Kammerer R, Velasco G, Marron M, Hellewell P & Ridger V (2017) . Scientific Reports, 7. RIS download Bibtex download
  • Hsiao ST, Spencer T, Boldock L, Prosseda SD, Xanthis I, Tovar-Lopez FJ, Van Beusekom HMM, Khamis RY, Foin N, Bowden N , Hussain A et al (2016) . Cardiovascular Research, 112(3), 689-701. RIS download Bibtex download
  • Serbanovic-Canic J, de Luca A, Warboys C, Ferreira PF, Luong LA, Hsiao S, Gauci I, Mahmoud M, Feng S, Souilhol C , Bowden N et al (2016) . Arteriosclerosis, Thrombosis, and Vascular Biology, 37(1), 130-143. RIS download Bibtex download
  • Bowden N, Bryan MT, Duckles H, Feng S, Hsiao S, Kim HR, Mahmoud M, Moers B, Serbanovic-Canic J, Xanthis I , Ridger VC et al (2016) . Antioxidants & Redox Signaling, 25(7), 389-400. RIS download Bibtex download
  • Mahmoud M, Kim HR, Xing R, Hsiao S, Mammmoto A, Chen J, Serbanovic-Canic J, Feng S, Bowden NP, Maguire R , Ariaans M et al (2016) . Circulation Research, 119, 450-462. RIS download Bibtex download
  • Duval C, Ali M, Chaudhry WW, Ridger VC, Ariëns RAS & Philippou H (2016) . Arteriosclerosis, Thrombosis, and Vascular Biology, 36(2), 308-316. RIS download Bibtex download
  • Domingues MM, Macrae FL, Duval C, McPherson HR, Bridge KI, Ajjan RA, Ridger VC, Connell SD, Philippou H & Ariens RAS (2016) . Blood, 127(4), 487-495. RIS download Bibtex download
  • Alfaidi M, Wilson H, Daigneault M, Burnett A, Ridger V, Chamberlain J & Francis SE (2015) . Journal of Biological Chemistry, 290, 24067-24078. RIS download Bibtex download
  • Alsharif KF, Thomas MR, Judge HM, Khan H, Prince LR, Sabroe I, Ridger VC & Storey RF (2015) . Vascular Pharmacology, 71, 201-207. RIS download Bibtex download
  • Ridger VC (2015) Neutrophils-derived-microvesicle Could Play a Role in the Early Stage of Atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology, 35. RIS download Bibtex download
  • Gomez I, Ward B, Evans P, Hellewell P & Ridger V (2015) . Arteriosclerosis, Thrombosis, and Vascular Biology, 35(suppl_1). RIS download Bibtex download
  • Alfaidi M, Wilson H, Ridger V, Chamberlain J & Francis S (2014) Neutrophil elastase enhances IL-1 beta secretion from coronary endothelium via an endolysosomal mediated mechanism, without caspase-1 activation. ANGIOGENESIS, 17(4), 941-941. RIS download Bibtex download
  • Duval C, Allan P, Connell SD, Ridger VC, Philippou H & Ariëns RA (2014) . Thrombosis and Haemostasis, 111(5), 842-850. RIS download Bibtex download
  • Alfaidi M, Wilson HL, Burnett A, Abdul-Aema BH, Ridger V, Chamberlain J & Francis SE (2014) . Heart, 100 Suppl 1, A2. RIS download Bibtex download
  • Duval C, Ridger VC, Philippou H & Ariens R (2013) Fibrinogen a-chain and ?-chain play specific roles in fibrin clot formation and structure. JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 11, 52-53. RIS download Bibtex download
  • Ali M, Ridger V, Pease R, Howells G, Grant P, Ariens R & Philippou H (2012) Establishment of method and image analysis systems to monitor clot formation and FXIII activity in real time using a murine in vivo model of thrombosis. JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 10(6), E14-E15. RIS download Bibtex download
  • Doyle EL, Ridger V, Ferraro F, Turmaine M, Saftig P & Cutler DF (2011) . Blood, 118(15), 4265-4273. RIS download Bibtex download
  • Ali M, Pease R, Ridger V, Howells G, Grant P, Ariens R & Philippou H (2011) Quantitative monitoring of clot formation and FXIII activity in real time using murine in vivo model of thrombosis. JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 9, 504-505. RIS download Bibtex download
  • La Corte ALC, Ali M, Glowacki R, Jakubowski H, Ridger V, Pease R, Scott J, Ariens RA & Philippou H (2011) In vivo N-homocysteinylation of fibrinogen and its role in thrombosis. JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 9, 142-142. RIS download Bibtex download
  • Halliday I, Atherton M, Care CM, Collins MW, Evans D, Evans PC, Hose DR, Khir AW, König CS, Krams R , Lawford PV et al (2011) . Medical Engineering and Physics, 33(7), 840-848. RIS download Bibtex download
  • Halliday I, Atherton M, Care CM, Collins MW, Evans D, Evans PC, Hose DR, Khir AW, König CS, Krams R , Lawford PV et al (2011) . Med Eng Phys, 33(7), 840-848. RIS download Bibtex download
  • Abbitt KB, Cotter MJ, Ridger VC, Crossman DC, Hellewell PG & Norman KE (2009) . J Leukoc Biol, 85(1), 55-63. RIS download Bibtex download
  • Ridger V, Krams R, Carpi A & Evans PC (2008) . Biomed Pharmacother, 62(8), 536-540. RIS download Bibtex download
  • Nolan S, Dixon R, Norman K, Hellewell P & Ridger V (2008) . Am J Pathol, 172(1), 265-273. RIS download Bibtex download
  • Ridger VC, Hellewell PG & Norman KE (2005) . Am J Pathol, 166(3), 945-952. RIS download Bibtex download
  • Hicks AER, Abbitt KB, Dodd P, Ridger VC, Hellewell PG & Norman KE (2005) . J Leukoc Biol, 77(1), 59-66. RIS download Bibtex download
  • Nolan SL, Norman KE, Hellewell PG & Ridger VC (2004) . Microcirculation, 11(6), 544-544. RIS download Bibtex download
  • Brown M, Bicknell R, Mortimer P, Levick J, Bates D, Wang W, Lu Y, Levick J, Joory K, Levick J , Mortimer P et al (2004) . Microcirculation, 11(6), 527-558. RIS download Bibtex download
  • Dockrell DH, Marriott HM, Prince LR, Ridger VC, Ince PG, Hellewell PG & Whyte MKB (2003) . J Immunol, 171(10), 5380-5388. RIS download Bibtex download
  • Hicks AER, Nolan SL, Ridger VC, Hellewell PG & Norman KE (2003) . Blood, 101(8), 3249-3256. RIS download Bibtex download
  • Rowe SJ, Allen L, Ridger VC, Hellewell PG & Whyte MKB (2002) . J Immunol, 169(11), 6401-6407. RIS download Bibtex download
  • Ridger VC, Hellewell PG & Norman KE (2002) sLe(x) can mediate rolling on P-selectin only in combination with L-selectin. FASEB J, 16(5), A1213-A1213. RIS download Bibtex download
  • Cotter MJ, Norman KE, Hellewell PG & Ridger VC (2001) . Am J Pathol, 159(2), 473-481. RIS download Bibtex download
  • Miotla JM, Ridger VC & Hellewell PG (2001) . Br J Pharmacol, 133(4), 550-556. RIS download Bibtex download
  • Ridger VC & Hellewell PG (2001) Differential effects of CD49 inhibition on CD18-dependent and independent neutrophil migration in pulmonary inflammation. FASEB J, 15(4), A328-A328. RIS download Bibtex download
  • Ridger VC, Wagner BE, Wallace WA & Hellewell PG (2001) . J Immunol, 166(5), 3484-3490. RIS download Bibtex download
  • Ridger VC & Hellewell PG (2000) A role for CD29 in CD18-independent neutrophil in mouse lungs. FASEB J, 14(4), A10-A10. RIS download Bibtex download
  • Hicks AE, Ridger VC, Dixon R, Dupr B, Hellewell PG & Norman KE (2000) Anti-inflammatory effects of TBC1269 are not due to competitive inhibition of leukocyte rolling. FASEB J, 14(4), A43-A43. RIS download Bibtex download
  • Cotter MJ, Norman KE, Hellewell PG & Ridger VC (2000) Negative selection of murine neutrophils from whole blood using antibody-conjugated magnetic beads. FASEB J, 14(4), A785-A785. RIS download Bibtex download
  • Greenacre S, Ridger V, Evans P, Halliwell B & Brain S (1999) Detection of nitrated proteins in peroxynitrite-treated rat skin and effects of nitrated plasma proteins on plasma extravasation. BRITISH JOURNAL OF PHARMACOLOGY, 126. RIS download Bibtex download
  • Greenacre S, Ridger V, Wilsoncroft P & Brain SD (1997) . Clin Exp Pharmacol Physiol, 24(11), 880-882. RIS download Bibtex download
  • Ridger VC, Greenacre SA, Handy RL, Halliwell B, Moore PK, Whiteman M & Brain SD (1997) . Br J Pharmacol, 122(6), 1083-1088. RIS download Bibtex download
  • Ridger VC, Pettipher ER, Bryant CE & Brain SD (1997) Effect of the inducible nitric oxide synthase inhibitors aminoguanidine and L-N6-(1-iminoethyl)lysine on zymosan-induced plasma extravasation in rat skin.. J Immunol, 159(1), 383-390. RIS download Bibtex download
  • Ridger VC & Brain SD (1996) Peroxynitrite induces plasma extravasation in rat dorsal skin. BRIT J PHARMACOL, 119, P56-P56. RIS download Bibtex download
  • Ridger VC & Brain SD (1996) The effect of L-N-6-(1-iminoethyl)lysine on zymosan-induced oedema in rat dorsal skin. BRIT J PHARMACOL, 117, P240-P240. RIS download Bibtex download
  • METZGER WJ, RIDGER V, TOLLEFSON V, ARRHENIUS T, GAETA FCA & ELICES M (1994) ANTI-VLA-4 ANTIBODY AND CS-1 PEPTIDE INHIBITOR MODIFIES AIRWAY INFLAMMATION AND BRONCHIAL AIRWAY HYPERRESPONSIVENESS (BHR) IN THE ALLERGIC RABBIT. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 93(1), 183-183. RIS download Bibtex download
  • Vázquez-Villaseñor I, Smith CI, Thang YJR, Heath PR, Wharton SB, Blackburn DJ, Ridger VC & Simpson JE () . International Journal of Molecular Sciences, 23(11), 5913-5913. RIS download Bibtex download
  • Xanthis I, Souilhol C, Serbanovic-Canic J, Roddie H, Kalli AC, Fragiadaki M, Wong R, Shah DR, Askari JA, Canham L , Akhtar N et al () . RIS download Bibtex download

Conference proceedings papers

  • Card E, Kiss-Toth E & Ridger V (2024) . Basic science RIS download Bibtex download
  • Almalki S, Kiss-Toth E & Ridger V (2024) . Basic science RIS download Bibtex download
  • Thang Y, Vazquez-Villasenor I, Smith C, Blackburn D, Wharton S, Heath P, Ridger V & Simpson J (2022) The miRNA profile of neutrophil-derived microvesicles may impact blood-brain barrier integrity in Alzheimer's disease. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, Vol. 48 RIS download Bibtex download
  • Long MB, Ajikumar A, Lodge K, Condliffe A & Ridger V (2019) . Airway cell biology and immunopathology RIS download Bibtex download
  • Long MB, Ajikumar A, Lodge K, Condliffe A & Ridger V (2019) . Airway Cell Biology and Immunopathology RIS download Bibtex download
  • Ward B, Gomez I, Willis J, Woods R, Parry S, Hulston C, Evans P & Ridger V (2017) . Atherosclerosis, Vol. 263 (pp e123-e124) RIS download Bibtex download
  • Gomez I, Ward B, Evans P, Hellewell P & Ridger V (2015) . Heart, Vol. 101(Suppl 4) (pp A122-A123), 8 June 2015 - 10 June 2015. RIS download Bibtex download
  • Gomez I, Ward B, Evans P, Hellewell P & Ridger V (2015) Abstract 558: Neutrophils-derived-microvesicle Could Play a Role in the Early Stage of Atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology, Vol. 35(Supp 1) (pp A558-A558) RIS download Bibtex download
  • Thomas MR, Alsharif KF, Prince LR, Ridger VC, Judge HM, Dockrell DH, Sabroe I & Storey RF (2015) . Journal of the American College of Cardiology, Vol. 65(10) (pp A259-A259) RIS download Bibtex download
  • Alsharif K, Judge H, Ridger V & Storey RF (2014) Ticagrelor and dipyridamole potentiate adenosine-induced stimulation of neutrophil chemotaxis in the presence of erythrocytes. EUROPEAN HEART JOURNAL, Vol. 35 (pp 1031-1032) RIS download Bibtex download
  • Burnett A, Daigneault M, Hellewell P & Ridger V (2013) . HEART, Vol. 99 RIS download Bibtex download
  • Angyal A, Daigneault M, Hadadi E, Ariaans M, Burnett A, Wilson H, Ridger V & Kiss-Toth E (2013) . HEART, Vol. 99 (pp A126-A126) RIS download Bibtex download
  • Burnett A, Hellewell P & Ridger V (2012) . HEART, Vol. 98 (pp A3-A4) RIS download Bibtex download
  • Ridger V (2008) Leukocyte-Endothelial Interactions with Respect to the Adhesion Cascade. BIOMEDICINE & PHARMACOTHERAPY, Vol. 62(8) (pp 504-504) RIS download Bibtex download
  • Nolan SL, Norman KE, Hellewell PG & Ridger VC (2003) Recombinant P-selectin glycoprotein ligand-1 binds to and inhibits the function of the murine chemokine KC in vitro. FASEB JOURNAL, Vol. 17(5) (pp A1071-A1071) RIS download Bibtex download

Preprints

  • McPherson HR, Duval C, Baker SR, Hindle MS, Cheah LT, Asquith NL, Domingues MM, Ridger VC, Connell SDA, Naseem KM , Philippou H et al () , Cold Spring Harbor Laboratory. RIS download Bibtex download
  • Souilhol C, Li X, Canham L, Roddie H, Pirri D, Ayllon BT, Chambers EV, Dunning MJ, Ariaans M, Li J , Fang Y et al () , Cold Spring Harbor Laboratory. RIS download Bibtex download
  • Gomez I, Ward B, Souilhol C, Recarti C, Ariaans M, Johnston J, Burnett A, Mahmoud M, Luong LA, West L , Long M et al () . RIS download Bibtex download
Research group

Supervisions

  • Miss Anjana Ajikumar
  • Mr Reece Dow
  • Miss Merete Long
  • Dr Taghreed Shamrani

Postdoctoral Research Associates

  • Dr Majid Ali
  • Dr Cedric Duval
Teaching activities

Postgraduate (Research):

Deputy Head of Department (PGR and Student Welfare) for the Department of Infection, Immunity & Cardiovascular Disease.
Year Tutor for all PGR students in the Medical School.

Postgraduate (Taught):

Course Lead for CDLT01 MRes in Cardiovascular Medicine: From Molecules to Man.
Module Lead for CDL402 Vascular Disease - Models & Clinical Practice.
Deputy Module Lead CDL602 Research Skills.

Undergraduate:

Non-clinical academic tutor for medical students.

Professional activities and memberships
  • Scientific Evaluation Board member of the European Research Area-CVD (2017-). Interview Panel member for British Heart Foundation Non-Clinical Fellowship (2016).
  • Member and Treasurer for UK Cell Adhesion Society (2017-), member of British Atherosclerosis Society (2015-) and International Society for Extracellular Vesicles (2016-). Associate member of ESC Working Group on Atherosclerosis and Vascular Biology (2018-)
  • Editorial board member for Scientific Reports (2018-), Pharmacology Research and Perspectives (2016-) and Journal of Inflammation (2016-2019).
  • External Examiner for Newcastle University (MRes in Cardiovascular Science in Health and Disease; 2019-